Gly-Pro-Arg-Pro Acetate

• CAT Number: I028159
• CAS Number: 67869-62-9
• Molecular Formula: C20H35N7O7
• Molecular Weight: 485.54
• Purity: 98%
• Synonyms: Gly-Pro-Arg-Pro Acetate; GPRP; Gly-Pro-Arg-Pro Acetate salt
• Target: Integrin
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid acetate
• InChI: InChI=1S/C18H31N7O5.C2H4O2/c19-10-14(26)24-8-2-5-12(24)15(27)23-11(4-1-7-22-18(20)21)16(28)25-9-3-6-13(25)17(29)30;1-2(3)4/h11-13H,1-10,19H2,(H,23,27)(H,29,30)(H4,20,21,22);1H3,(H,3,4)/t11-,12-,13-;/m0./s1
• InChIKey: ZYTSTPIIKNCGRE-QKWXXBCPSA-N
• SMILES: O=C([C@H]1N(C([C@@H](NC([C@H]2N(C(CN)=O)CCC2)=O)CCCNC(N)=N)=O)CCC1)O.CC(O)=O

Gly-Pro-Arg-Pro Acetate is an inhibitor of fibrinogen aggregation that acts by binding to fibrinopeptide A.

Reference

1: Redlich H, Vickers J, Lösche W, Heptinstall S, Kehrel B, Spangenberg P. Formation of platelet-leukocyte conjugates in whole blood. Platelets. 1997;8(6):419-25. PubMed PMID: 16793677.
2: Ouyang XL, Liu JH, Luo Q, Shi Q, Han W, Li XJ, Gao D. [Flow cytometry combined assay for phosphatidylserine and CD62p expressed by preserved platelets]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2002 Feb;10(1):66-9. Chinese. PubMed PMID: 12513841.