Glycolic acid oxidase inhibitor 1

• CAT Number: I020224
• CAS Number: 77529-42-1
• Molecular Formula: C16H10BrNO3
• Molecular Weight: 344.16
• Purity: ≥95%
• Synonyms: 3-[4-(4-bromophenyl)phenyl]-4-hydroxypyrrole-2,5-dione
• InChI: InChI=1S/C16H10BrNO3/c17-12-7-5-10(6-8-12)9-1-3-11(4-2-9)13-14(19)16(21)18-15(13)20/h1-8H,(H2,18,19,20,21)
• InChIKey: WMLWRZOUOGMDNS-UHFFFAOYSA-N
• SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)Br)C3=C(C(=O)NC3=O)O

Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.
Glycolic acid oxidase inhibitor 1 inhibits oxalate biosynthesis in isolated perfused rat liver. Glycolate oxidase inhibitors provide a specific approach to the prevention and treatment of calcium oxalate renal lithiasis[1].

Reference

[1]. Cragoe Jr., Edward J, et al. 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same.EP0021228A1.