Glycolithocholate sulfate

• CAT Number: M077496
• CAS Number: 15324-64-8
• Molecular Formula: C26H43NO7S
• Molecular Weight: 513.69
• Purity: ≥95%
• Synonyms: Sulfoglycolithocholic acid
• Target: Metabolic Enzyme/Protease
• Storage: Store at -20°C
• IUPAC Name: 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
• InChI: InChI=1S/C26H43NO7S/c1-16(4-9-23(28)27-15-24(29)30)20-7-8-21-19-6-5-17-14-18(34-35(31,32)33)10-12-25(17,2)22(19)11-13-26(20,21)3/h16-22H,4-15H2,1-3H3,(H,27,28)(H,29,30)(H,31,32,33)/t16-,17-,18-,19+,20-,21+,22+,25+,26-/m1/s1
• InChIKey: FHXBAFXQVZOILS-OETIFKLTSA-N
• SMILES: CC(CCC(=O)NCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)OS(=O)(=O)O)C)C

Glycolithocholate sulfate is a conjugated bile acid derivative formed by the sulfation of glycolithocholic acid. It plays a role in the metabolism and excretion of bile acids, particularly as part of the body’s mechanism for eliminating potentially toxic bile acids from the liver. Sulfation increases the solubility of bile acids, facilitating their removal through bile or urine. Glycolithocholate sulfate has been studied for its involvement in cholestatic liver diseases, where the accumulation of bile acids can lead to liver damage. It is also important in understanding bile acid homeostasis and its effects on liver function and overall digestive health.