Glycolithocholic acid 3-sulfate disodium

• CAT Number: R017944
• CAS Number: 64936-82-9
• Molecular Formula: C26H41NNa2O7S
• Molecular Weight: 557.65
• Purity: ≥95%
• Synonyms: disodium;2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3-sulfonatooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetate
• InChI: InChI=1S/C26H43NO7S.2Na/c1-16(4-9-23(28)27-15-24(29)30)20-7-8-21-19-6-5-17-14-18(34-35(31,32)33)10-12-25(17,2)22(19)11-13-26(20,21)3;;/h16-22H,4-15H2,1-3H3,(H,27,28)(H,29,30)(H,31,32,33);;/q;2*+1/p-2/t16-,17-,18-,19+,20-,21+,22+,25+,26-;;/m1../s1
• InChIKey: FXMCQRUEVPOMSC-DJOVSRRHSA-L
• SMILES: CC(CCC(=O)NCC(=O)[O-])C1CCC2C1(CCC3C2CCC4C3(CCC(C4)OS(=O)(=O)[O-])C)C.[Na+].[Na+]

Glycolithocholic acid 3-sulfate (disodium) inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate (disodium) can be used for the research of HIV infection and gallbladder disease[1][2].

Reference

[1]. Baba M, et al. Selective activity of several
cholic acid derivatives against human immunodeficiency virus replication in
vitro. J Acquir Immune Defic Syndr (1988). 1989;2(3):264-271.
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[2]. I M Yousef, et al. Lithocholate cholestasis–sulfated glycolithocholate-induced intrahepatic cholestasis in rats. Gastroenterology. 1981 Feb;80(2):233-41.
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