Glycyrrhizic Acid

For research use only. Not for therapeutic Use.

  • CAT Number: R058312
  • CAS Number: 1405-86-3
  • Molecular Formula: C42H62O16
  • Molecular Weight: 822.93
  • Purity: ≥95%
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Glycyrrhizic Acid(Cat No.:R058312)is a bioactive compound derived from Glycyrrhiza glabra (licorice root), known for its anti-inflammatory, antioxidant, and antimicrobial properties. It is commonly used in traditional medicine for treating respiratory, digestive, and skin conditions. Glycyrrhizic acid functions as an inhibitor of 11β-hydroxysteroid dehydrogenase type 2, which can increase cortisol levels. It has potential therapeutic applications in treating viral infections, reducing symptoms of chronic hepatitis, and alleviating inflammatory disorders. Glycyrrhizic acid is also studied for its ability to enhance drug absorption and improve skin barrier function.


Catalog Number R058312
CAS Number 1405-86-3
Synonyms

(3β,20β)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-β-D-Glucopyranuronosyl-α-?D-glucopyranosiduronic Acid; 18β-Glycyrrhizic Acid; 18β-Glycyrrhizinic Acid; Glycyron; Glycyrrhetinic Acid Glycoside; Glycyrrhizin; Glycyrrhizinic Acid; NSC 167409; NSC 2

Molecular Formula C42H62O16
Purity ≥95%
Target 11 beta-hydroxysteroid dehydrogenase
Storage 3 years -20C powder
IUPAC Name (2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
InChI InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1
InChIKey LPLVUJXQOOQHMX-QWBHMCJMSA-N
SMILES C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O

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