Glyoxalase I inhibitor 3

• CAT Number: I043611
• CAS Number: 1415388-25-8
• Molecular Formula: C22H21N3O3
• Molecular Weight: 375.42
• Purity: ≥95%
• Synonyms: 1-hydroxy-6-[1-(3-methoxypropyl)pyrrolo[2,3-b]pyridin-5-yl]-4-phenyl-3,4-dihydropyridin-2-one
• IUPAC Name: 1-hydroxy-6-[1-(3-methoxypropyl)pyrrolo[2,3-b]pyridin-5-yl]-4-phenylpyridin-2-one
• InChI: InChI=1S/C22H21N3O3/c1-28-11-5-9-24-10-8-17-12-19(15-23-22(17)24)20-13-18(14-21(26)25(20)27)16-6-3-2-4-7-16/h2-4,6-8,10,12-15,27H,5,9,11H2,1H3
• InChIKey: MIWLVFZOCHMICD-UHFFFAOYSA-N
• SMILES: COCCCN1C=CC2=CC(=CN=C21)C3=CC(=CC(=O)N3O)C4=CC=CC=C4

Glyoxalase I inhibitor 3 (Cat No.:I043611) is a small molecule compound that targets and inhibits the activity of the glyoxalase I enzyme. This enzyme plays a crucial role in the detoxification of reactive dicarbonyl species, particularly methylglyoxal, a byproduct of metabolism linked to oxidative stress and various diseases, including diabetes and neurodegenerative conditions. By inhibiting glyoxalase I, GloI-3 aims to enhance the accumulation of methylglyoxal, which may disrupt cellular function in certain cancer cells. As a result, GloI-3 holds potential as a therapeutic approach in cancer and other diseases associated with altered glyoxalase I activity.