For research use only. Not for therapeutic Use.
Glyoxalase I inhibitor 6 (Compound 9j) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 1.13 μM. Glyoxalase I inhibitor 6 can be used as anticancer agent with low toxicity[1].
| Catalog Number | I043656 |
| CAS Number | 2455508-19-5 |
| Synonyms | 1-hydroxy-4-[(4-methyl-3-sulfamoylphenyl)diazenyl]naphthalene-2-carboxylic acid |
| Molecular Formula | C18H15N3O5S |
| Purity | ≥95% |
| InChI | InChI=1S/C18H15N3O5S/c1-10-6-7-11(8-16(10)27(19,25)26)20-21-15-9-14(18(23)24)17(22)13-5-3-2-4-12(13)15/h2-9,22H,1H3,(H,23,24)(H2,19,25,26) |
| InChIKey | DXHDPHYZULAOTP-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)N=NC2=CC(=C(C3=CC=CC=C32)O)C(=O)O)S(=O)(=O)N |
| Reference | [1]. Al-Oudat BA, et al. Design, synthesis and biological evaluation of novel glyoxalase I inhibitors possessing diazenylbenzenesulfonamide moiety as potential anticancer agents. Bioorg Med Chem. 2020 Aug 15;28(16):115608. |
