For research use only. Not for therapeutic Use.
Goitrin is a constituent of Radix isatidis (Banlangen), which is a widely used traditional Chinese medicine for treating fever and removing toxic heat. Goitrin is known as an antithyroid factor, but also exhibits antiviral activity.
Note: Some suppliers are selling DL-Goitrin (racemate, CAS 13190-34-6) as Goitrin and what we provide is the optically pure Goitrin (L-Goitrin, CAS 500-12-9, CID: 7568320). The opposite enantiomer, optically pure Epigoitrin (Axon 3782) is also available from Axon Medchem.
KEYWORDS: Goitrin (optically pure) | Supplier | Antithyroid factor | (S)-Goitrin | CAS [500-12-9]
| Catalog Number | I047697 |
| CAS Number | 500-12-9 |
| Molecular Formula | C5H7NOS |
| Purity | ≥95% |
| IUPAC Name | (5S)-5-ethenyl-1,3-oxazolidine-2-thione |
| InChI | InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m0/s1 |
| SMILES | C=C[C@H]1CNC(=S)O1 |
| Reference | L Nie et al. Antiviral activity of Isatidis Radix derived glucosinolate isomers and their breakdown products against influenza A in vitro/ovo and mechanism of action. J Ethnopharmacol. 2020 Apr 6;251:112550. L Nie et al. Stereospecific Assay of (R)- and (S)-Goitrin in Commercial Formulation of Radix Isatidis by Reversed Phase High-Performance Liquid Chromatography. J Anal Methods Chem. 2017;2017:2810565. |
