Golgicide A-1

• CAT Number: I045706
• CAS Number: 1394285-49-4
• Molecular Formula: C17H14F2N2
• Molecular Weight: 284.30
• Purity: ≥95%
• Synonyms: (3aR,4S,9bS)-6,8-difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
• InChI: InChI=1S/C17H14F2N2/c18-11-7-14-12-4-1-5-13(12)16(10-3-2-6-20-9-10)21-17(14)15(19)8-11/h1-4,6-9,12-13,16,21H,5H2/t12-,13+,16+/m0/s1
• InChIKey: NJZHEQOUHLZCOX-WOSRLPQWSA-N
• SMILES: C1C=CC2C1C(NC3=C2C=C(C=C3F)F)C4=CN=CC=C4

Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction[1].
Golgicide A-1 (GCA-1) displays minimal to no cytotoxicity in the Aedes aegypti and Anopheles stephensi larvae assay[1].

Reference

[1]. Daniel J Mack, et al. Distinct biological effects of golgicide a derivatives on larval and adult mosquitoes. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5177-81.
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