Golgicide A

• CAT Number: R051134
• CAS Number: 1139889-93-2
• Molecular Formula: C17H14F2N2
• Molecular Weight: 284.30
• Purity: ≥95%
• Synonyms: (3aR,9bS)-rel-6,8-Difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]?quinoline
• Target: Enterovirus
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at -20℃
• IUPAC Name: (3aR,9bS)-6,8-difluoro-4-pyridin-3-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline
• InChI: InChI=1S/C17H14F2N2/c18-11-7-14-12-4-1-5-13(12)16(10-3-2-6-20-9-10)21-17(14)15(19)8-11/h1-4,6-9,12-13,16,21H,5H2/t12-,13+,16?/m0/s1
• InChIKey: NJZHEQOUHLZCOX-FTLRAWMYSA-N
• SMILES: C1C=C[C@H]2[C@@H]1C(NC3=C2C=C(C=C3F)F)C4=CN=CC=C4

Golgicide A（Cat No.:R051134）is a potent inhibitor of Golgi complex function, particularly targeting the retrograde transport of proteins from the Golgi to the endoplasmic reticulum (ER). It disrupts the Golgi’s structure and function by inhibiting the Golgi apparatus’s vesicle transport mechanisms, leading to the accumulation of proteins in the ER. This compound is of great interest in cell biology and drug discovery for its potential to explore the role of Golgi dynamics in cellular processes. Golgicide A also demonstrates possible applications in cancer therapy and disease modeling related to protein trafficking.