Gomisin M1

• CAT Number: R004034
• CAS Number: 82467-50-3
• Molecular Formula: C22H26O6
• Molecular Weight: 386.44
• Purity: ≥95%
• Synonyms: 4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-3-ol
• InChI: InChI=1S/C22H26O6/c1-11-6-13-8-15(24-3)20(25-4)19(23)17(13)18-14(7-12(11)2)9-16-21(22(18)26-5)28-10-27-16/h8-9,11-12,23H,6-7,10H2,1-5H3
• InChIKey: OGJPBGDUYKEQLA-UHFFFAOYSA-N
• SMILES: CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)O)OC)OCO3

Gomisin M1 ((±)-Gomisin M1) is a potent anti-HIV agent with an EC50 of <0.65 μM[1].
Gomisin M1 ((±)-Gomisin M1) (4 days) shows anti-HIV-1 activity with an EC50 of <0.65 μM in H9 T cell lines and therapeutic index (TI) is >68[1].

Reference

[1]. Chen M, et al. Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora. J Nat Prod. 2006 Dec;69(12):1697-701.
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