Goralatide TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I043726
  • CAS Number: 1796568-94-9
  • Molecular Formula: C22H34F3N5O11
  • Molecular Weight: 601.53
  • Purity: ≥95%
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Goralatide TFA is an inhibitor of cell cycle progression. Goralatide TFA enhances selectivity of hyperthermic purging of human progenitor cells. Goralatide TFA has the potential for the research of leukemia[1].


Catalog Number I043726
CAS Number 1796568-94-9
Synonyms

(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid;2,2,2-trifluoroacetic acid

Molecular Formula C22H34F3N5O11
Purity ≥95%
InChI InChI=1S/C20H33N5O9.C2HF3O2/c1-11(27)22-14(10-26)18(31)24-13(9-16(28)29)17(30)23-12(5-2-3-7-21)19(32)25-8-4-6-15(25)20(33)34;3-2(4,5)1(6)7/h12-15,26H,2-10,21H2,1H3,(H,22,27)(H,23,30)(H,24,31)(H,28,29)(H,33,34);(H,6,7)/t12-,13-,14-,15-;/m0./s1
InChIKey LKOFRAPICMDYPN-WFGXUCIJSA-N
SMILES CC(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O.C(=O)(C(F)(F)F)O
Reference

[1]. Wierenga PK, et al. Enhanced selectivity of hyperthermic purging of human progenitor cells using Goralatide, an inhibitor of cell cycle progression. Bone Marrow Transplant. 1998;21(1):73-78.
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