Goserelin

For research use only. Not for therapeutic Use.

  • CAT Number: I004480
  • CAS Number: 65807-02-5
  • Molecular Formula: C59H84N18O14
  • Molecular Weight: 1269.41
  • Purity: ≥95%
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Goserelin(Cat No.:I004480)is a synthetic analogue of gonadotropin-releasing hormone (GnRH), used in hormone therapy for conditions like prostate cancer, breast cancer, and endometriosis. It works by initially stimulating, then suppressing, the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to reduced levels of testosterone in men and estrogen in women. This hormone suppression slows the growth of hormone-sensitive tumors and alleviates symptoms of endometriosis. Goserelin is administered as a long-acting subcutaneous implant, providing sustained therapeutic effects for cancer and reproductive health management.


Catalog Number I004480
CAS Number 65807-02-5
Molecular Formula C59H84N18O14
Purity ≥95%
Target GnRH
Solubility 10 mM in DMSO
Storage Store at -20°C
IUPAC Name (2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
InChI InChI=1S/C59H84N18O14/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90)/t38-,39-,40-,41-,42-,43-,44-,45+,46-/m0/s1
InChIKey BLCLNMBMMGCOAS-URPVMXJPSA-N
SMILES CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NNC(=O)N)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6
Reference

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<br>[1]. Goserelin, From Wikipedia
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