For research use only. Not for therapeutic Use.
GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. GPR132 antagonist 1 has promote insulin secretion activity with an EC50 value of 0.7 μM[1].
| Catalog Number | I040166 |
| CAS Number | 898211-21-7 |
| Synonyms | 3-methyl-5-(2-phenylethylsulfamoyl)-1-benzofuran-2-carboxylic acid |
| Molecular Formula | C18H17NO5S |
| Purity | ≥95% |
| InChI | InChI=1S/C18H17NO5S/c1-12-15-11-14(7-8-16(15)24-17(12)18(20)21)25(22,23)19-10-9-13-5-3-2-4-6-13/h2-8,11,19H,9-10H2,1H3,(H,20,21) |
| InChIKey | XFMCZHXUAWBOAL-UHFFFAOYSA-N |
| SMILES | CC1=C(OC2=C1C=C(C=C2)S(=O)(=O)NCCC3=CC=CC=C3)C(=O)O |
| Reference | [1]. 焦宁, 等. Gpcr调节剂及其应用. 专利. CN116903563A. |
