GPR35 agonist 1

For research use only. Not for therapeutic Use.

  • CAT Number: I018786
  • CAS Number: 2079880-92-3
  • Molecular Formula: C10H4BrN5O5
  • Molecular Weight: 354.07
  • Purity: ≥95%
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GPR35 agonist 1 (compound 50) is a potent and specific G protein-coupled receptor-35 (GPR35)/CXCR8 agonist with an EC50 of 5.8 nM, displays good agentgability[1].


Catalog Number I018786
CAS Number 2079880-92-3
Synonyms

6-bromo-7-hydroxy-8-nitro-3-(2H-tetrazol-5-yl)chromen-2-one

Molecular Formula C10H4BrN5O5
Purity ≥95%
InChI InChI=1S/C10H4BrN5O5/c11-5-2-3-1-4(9-12-14-15-13-9)10(18)21-8(3)6(7(5)17)16(19)20/h1-2,17H,(H,12,13,14,15)
InChIKey AQJFPDDDKBWBAG-UHFFFAOYSA-N
SMILES C1=C2C=C(C(=O)OC2=C(C(=C1Br)O)[N+](=O)[O-])C3=NNN=N3
Reference

[1]. Wei L, et al. Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists. J Med Chem. 2017 Jan 12;60(1):362-372.
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