For research use only. Not for therapeutic Use.
GPR35 agonist 2 (compound 11) is a potent agonist of GPR35, with EC50s of 26 and 3.2 nM in the β-arrestin and Ca2+ release assay, respectively[1].
| Catalog Number | I011046 |
| CAS Number | 494191-73-0 |
| Synonyms | 4-[(E)-[2-(2-fluorophenyl)imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]benzoic acid |
| Molecular Formula | C17H11FN2O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H11FN2O3S/c18-12-3-1-2-4-13(12)19-17-20-15(21)14(24-17)9-10-5-7-11(8-6-10)16(22)23/h1-9H,(H,22,23)(H,19,20,21)/b14-9+ |
| InChIKey | SYCKPHBALHXMIR-NTEUORMPSA-N |
| SMILES | C1=CC=C(C(=C1)N=C2NC(=O)C(=CC3=CC=C(C=C3)C(=O)O)S2)F |
| Reference | [1]. Thimm D, et, al. 6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35. J Med Chem. 2013 Sep 12; 56(17): 7084-99. |
