GPR35 agonist 4

• CAT Number: I010924
• CAS Number: 871085-49-3
• Molecular Formula: C12H9NO5S
• Molecular Weight: 279.27
• Purity: ≥95%

GPR35 agonist 4 (compound 10) is a potent GPR35 agonist with an pEC50 of 5.86. GPR35 agonist 4 shows high potency human and rat GPR35. Mutation of arginine 3.36 eliminates agonist function of GPR35 agonist 4[1].

Reference

[1]. Jenkins L, et al. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2. Br J Pharmacol. 2011 Feb;162(3):733-48.
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