GPR40/FFAR1 modulator 1

• CAT Number: I046216
• CAS Number: 874755-26-7
• Molecular Formula: C21H19N5O3
• Molecular Weight: 389.41
• Purity: ≥95%
• Synonyms: 7-[[4-amino-6-(2-methylanilino)-1,3,5-triazin-2-yl]methoxy]-4-methylchromen-2-one
• InChI: InChI=1S/C21H19N5O3/c1-12-5-3-4-6-16(12)23-21-25-18(24-20(22)26-21)11-28-14-7-8-15-13(2)9-19(27)29-17(15)10-14/h3-10H,11H2,1-2H3,(H3,22,23,24,25,26)
• InChIKey: WCRLDDWRDAIHGO-UHFFFAOYSA-N
• SMILES: CC1=CC=CC=C1NC2=NC(=NC(=N2)N)COC3=CC4=C(C=C3)C(=CC(=O)O4)C

GPR40/FFAR1 modulator 1 is an agonist and an allosteric modulator for Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1)[1].

Reference

[1]. Lückmann M, et al. Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7123-7128.
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