GPX100

For research use only. Not for therapeutic Use.

  • CAT Number: I007020
  • CAS Number: 952648-77-0
  • Molecular Formula: C27H31NO10
  • Molecular Weight: 529.54
  • Purity: ≥95%
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GPX-100 is a n analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. GPX-100 was designed to be a non


Catalog Number I007020
CAS Number 952648-77-0
Synonyms

GPX100; GPX 100; GPX-100; 13deoxydoxorubicin.;(8R,10S)-10-(((2S,4S,5R,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyethyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Molecular Formula C27H31NO10
Purity ≥95%
Solubility Soluble in DMSO, not in water
Storage 0 - 4 °C for short term or -20 °C for long term
SMILES O=C1C2=C(O)C(C[C@](CCO)(O)C[C@@H]3O[C@@H]4C[C@H](N)[C@@H](O)[C@H](C)O4)=C3C(O)=C2C(C5=C1C=CC=C5OC)=O
Reference

</br>1: Slupe A, Williams B, Larson C, Lee LM, Primbs T, Bruesch AJ, Bjorklund C, Warner DL, Peloquin J, Shadle SE, Gambliel HA, Cusack BJ, Olson RD, Charlier HA Jr. Reduction of 13-deoxydoxorubicin and daunorubicinol anthraquinones by human carbonyl

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