GR-65630

• CAT Number: I012607
• CAS Number: 117186-80-8
• Molecular Formula: C16H17N3O
• Molecular Weight: 267.33
• Purity: ≥95%
• Synonyms: 3-(5-Methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol-3-yl)-1-propanone
• IUPAC Name: 3-(5-methyl-1H-imidazol-4-yl)-1-(1-methylindol-2-yl)propan-1-one
• InChI: InChI=1S/C16H17N3O/c1-11-13(18-10-17-11)7-8-16(20)15-9-12-5-3-4-6-14(12)19(15)2/h3-6,9-10H,7-8H2,1-2H3,(H,17,18)
• InChIKey: AQCBJPZFJDPIGL-UHFFFAOYSA-N
• SMILES: CC1=C(N=CN1)CCC(=O)C2=CC3=CC=CC=C3N2C

GR-65630（Cat No.:I012607）is a selective antagonist of the glucagon-like peptide-1 (GLP-1) receptor, which plays a key role in regulating glucose metabolism, insulin secretion, and appetite. By blocking the GLP-1 receptor, GR-65630 can inhibit the effects of GLP-1, including its ability to stimulate insulin release and suppress glucagon secretion, which are important for controlling blood sugar levels. This makes GR-65630 a potential candidate for research into diabetes and obesity treatments, particularly in conditions where GLP-1 signaling is overly active. Further clinical studies are necessary to evaluate its safety and therapeutic potential.