GR148672X

• CAT Number: I007027
• CAS Number: 263890-70-6
• Molecular Formula: C15H11F3N2O2S
• Molecular Weight: 340.32
• Purity: ≥95%
• Synonyms: GR148672X; GR-148672X; GR 148672X.;(2E)-4,4,4-trifluoro-2-[(3-methylphenyl)hydrazinylidene]-1-thiophen-2-ylbutane-1,3-dione
• Solubility: Soluble in DMSO
• Storage: 2–8 °C
• IUPAC Name: (E)-1,1,1-trifluoro-4-hydroxy-3-[(3-methylphenyl)diazenyl]-4-thiophen-2-ylbut-3-en-2-one
• InChI: InChI=1S/C15H11F3N2O2S/c1-9-4-2-5-10(8-9)19-20-12(14(22)15(16,17)18)13(21)11-6-3-7-23-11/h2-8,21H,1H3/b13-12+,20-19?
• InChIKey: OETQEFUTOKYBSL-KJTMXWSCSA-N
• SMILES: CC1=CC(=CC=C1)N=NC(=C(C2=CC=CS2)O)C(=O)C(F)(F)F

GR148672X（Cat No.: I007027）, is a potent inhibitor of triacylglycerol hydrolase (TGH). Its inhibitory activity is notable, with an IC50 value of 4 nM, as documented in patent WO 2001016358 A2. TGH plays a crucial role in lipid metabolism, particularly in the breakdown of triacylglycerols. By inhibiting TGH, GR148672X may have potential applications in the regulation of lipid metabolism and related pathways. This compound’s high potency positions it as a valuable tool in research exploring the roles of TGH and lipid metabolism in various physiological and pathological processes. If you need to, please contact us in time, and we will reply to you as soon as possible within 24 hours.