GRA Ex-25

• CAT Number: I003090
• CAS Number: 307983-31-9
• Molecular Formula: C29H36F3N3O5
• Molecular Weight: 563.61
• Purity: ≥95%
• Target: GCGR
• Solubility: DMSO: ≥ 32 mg/mL
• Storage: Store at -20℃
• IUPAC Name: 3-[[4-[[(4-tert-butylcyclohexyl)-[[4-(trifluoromethoxy)phenyl]carbamoyl]amino]methyl]benzoyl]amino]propanoic acid
• InChI: InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)
• InChIKey: BZXMLCVDKDXRQY-UHFFFAOYSA-N
• SMILES: CC(C)(C)C1CCC(CC1)N(CC2=CC=C(C=C2)C(=O)NCCC(=O)O)C(=O)NC3=CC=C(C=C3)OC(F)(F)F

GRA Ex-25 (Cat.No:I003090) is a peptide compound used in medical research. It belongs to the class of glucagon-like peptide-1 (GLP-1) receptor agonists. GRA Ex-25 has shown potential in regulating blood sugar levels and promoting weight loss. It is being investigated as a potential treatment for type 2 diabetes and obesity.

Reference

[1]. /Kurukulasuriya R, et al. Biaryl amide glucagon receptor antagonists. Bioorg Med Chem Lett. 2004 May 3;14(9):2047-50.
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[2]. /Lau J, et al. New beta-alanine derivatives are orally available glucagon receptor antagonists. J Med Chem. 2007 Jan 11;50(1):113-28.
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