For research use only. Not for therapeutic Use.
Granisetron HCl (Cat No.: A000463) is a selective serotonin 5-HT3 receptor antagonist used to prevent and treat nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. It works by blocking serotonin receptors in the gut and the central nervous system, which are involved in triggering the vomiting reflex. Administered orally, intravenously, or via transdermal patch, granisetron is generally well-tolerated. Common side effects include headache, constipation, and fatigue. It offers a long duration of action and is effective in both acute and delayed nausea.
| CAS Number | 107007-99-8 |
| Synonyms | NA |
| Molecular Formula | C18H24N4O • HCl |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Limited solubility |
| Storage | 3 years -20C powder |
| IUPAC Name | 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide;hydrochloride |
| InChI | 1S/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H/t12?,13-,14+; |
| InChIKey | QYZRTBKYBJRGJB-WQTKJZBYSA-N |
| SMILES | CN1[C@@H]2CCC[C@H]1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
