For research use only. Not for therapeutic Use.
GRGESP is a collagen gel contraction inhibitor. GRGESP inhibits the spreading of human fibroblasts inside collagen gels and markedly decreased gel contraction. GRGDSP can be used for the research of connective tissue morphogenesis[1].
GRGESP inhibits the spreading of human fibroblasts inside collagen gels and markedly decreased gel contraction[1].
GRGDSP inhibits cell spreading on collagen-coated surfaces[1].
| Catalog Number | I042702 |
| CAS Number | 99896-88-5 |
| Synonyms | (2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-carboxybutanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carboxylic acid |
| Molecular Formula | C23H39N9O10 |
| Purity | ≥95% |
| InChI | InChI=1S/C23H39N9O10/c24-9-16(34)29-12(3-1-7-27-23(25)26)19(38)28-10-17(35)30-13(5-6-18(36)37)20(39)31-14(11-33)21(40)32-8-2-4-15(32)22(41)42/h12-15,33H,1-11,24H2,(H,28,38)(H,29,34)(H,30,35)(H,31,39)(H,36,37)(H,41,42)(H4,25,26,27)/t12-,13-,14-,15-/m0/s1 |
| InChIKey | AGOOUZZBQZNYCU-AJNGGQMLSA-N |
| SMILES | C1CC(N(C1)C(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)NC(=O)CN)C(=O)O |
| Reference | [1]. F Grinnell, et al. The collagen recognition sequence for fibroblasts depends on collagen topography. Exp Cell Res. 1989 Jun;182(2):668-72. |
