GRK2 Inhibitor 1

• CAT Number: R040855
• CAS Number: 24269-96-3
• Molecular Formula: C12H9NO6
• Molecular Weight: 263.20
• Purity: ≥95%
• Synonyms: methyl 5-[(E)-2-(5-nitrofuran-2-yl)ethenyl]furan-2-carboxylate
• InChI: InChI=1S/C12H9NO6/c1-17-12(14)10-6-4-8(18-10)2-3-9-5-7-11(19-9)13(15)16/h2-7H,1H3/b3-2+
• InChIKey: YDJPHSNZGRVPCK-NSCUHMNNSA-N
• SMILES: COC(=O)C1=CC=C(O1)C=CC2=CC=C(O2)[N+](=O)[O-]

GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor[1].

Reference

[1]. Nimitvilai S, et al. Reversal of dopamine D2 agonist-induced inhibition of ventral tegmental area neurons by Gq-linked neurotransmitters is dependent on protein kinase C, G protein-coupled receptor kinase, and dynamin. J Pharmacol Exp Ther. 2013 Jan;344(1
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