GS39783（Cat No.:R042422）is a selective antagonist of the GABA-B receptor, a G-protein-coupled receptor involved in inhibitory neurotransmission in the central nervous system. By blocking the activity of this receptor, GS39783 has been investigated for its potential therapeutic effects in treating disorders related to excessive neurotransmission, such as anxiety, depression, and addiction. Its ability to modulate neurotransmitter release and reduce hyperactivity in neural circuits makes it a promising candidate for addressing neurological and psychiatric conditions. GS39783 is still under investigation, with ongoing studies exploring its efficacy and safety profile in various therapeutic areas.