For research use only. Not for therapeutic Use.
GS39783 is a positive allosteric modulator (PAM) of GABABR. Positive modulation of the GABABR can be used for the research of Nicotine addiction[1].
| Catalog Number | R042422 |
| CAS Number | 39069-52-8 |
| Synonyms | 4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine |
| Molecular Formula | C15H23N5O2S |
| Purity | ≥95% |
| InChI | InChI=1S/C15H23N5O2S/c1-23-15-18-13(16-10-6-2-3-7-10)12(20(21)22)14(19-15)17-11-8-4-5-9-11/h10-11H,2-9H2,1H3,(H2,16,17,18,19) |
| InChIKey | GSGVDKOCBKBMGG-UHFFFAOYSA-N |
| SMILES | CSC1=NC(=C(C(=N1)NC2CCCC2)[N+](=O)[O-])NC3CCCC3 |
| Reference | [1]. Emmanuel Sturchler, et al. GABA B receptor allosteric modulators exhibit pathway-dependent and species-selective activity. Pharmacol Res Perspect. 2017 Mar 24;5(2):e00288. |
