For research use only. Not for therapeutic Use.
GS967(Cat No.:I001057) is a selective and potent inhibitor of the late sodium current (INaL) in cardiac cells, making it a valuable tool in cardiovascular research. By reducing sodium overload, GS967 helps restore normal cellular ion homeostasis and is studied for its antiarrhythmic properties. It has shown promise in treating conditions like ventricular arrhythmias and long QT syndrome. GS967 is also used to explore the role of late sodium currents in cardiac pathophysiology, offering insights into potential therapeutic strategies for heart rhythm disorders.
Catalog Number | I001057 |
CAS Number | 1262618-39-2 |
Synonyms | 6-(4-(trifluoromethoxy)phenyl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine |
Molecular Formula | C14H7F6N3O |
Purity | ≥95% |
Target | Sodium Channel |
Solubility | 10 mM in DMSO |
Storage | Store at -20°C |
IUPAC Name | 6-[4-(trifluoromethoxy)phenyl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine |
InChI | InChI=1S/C14H7F6N3O/c15-13(16,17)12-22-21-11-6-3-9(7-23(11)12)8-1-4-10(5-2-8)24-14(18,19)20/h1-7H |
InChIKey | FEVBKJITJDHASC-UHFFFAOYSA-N |
SMILES | C1=CC(=CC=C1C2=CN3C(=NN=C3C(F)(F)F)C=C2)OC(F)(F)F |