GSK-3β inhibitor 1

• CAT Number: I019149
• CAS Number: 187325-53-7
• Molecular Formula: C14H10N2O
• Molecular Weight: 222.25
• Purity: ≥95%

GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].

Reference

[1]. Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.
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