GSK LSD1 Dihydrochloride-d4

• CAT Number: R030311
• CAS Number: NA
• Molecular Formula: C₁₄H₁₈D₄Cl₂N₂
• Molecular Weight: 293.27
• Purity: ≥95%
• Synonyms: N-((1R,2S)-2-Phenylcyclopropyl)piperidin-4-amine Dihydrochloride-d4
• Storage: -20°C
• IUPAC Name: 3,3,5,5-tetradeuterio-N-[(1R,2S)-2-phenylcyclopropyl]piperidin-4-amine
• InChI: InChI=1S/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/m0/s1/i6D2,7D2
• InChIKey: BASFYRLYJAZPPL-WPCNBRCMSA-N
• SMILES: [2H]C1(CNCC(C1N[C@@H]2C[C@H]2C3=CC=CC=C3)([2H])[2H])[2H]

GSK LSD1 Dihydrochloride-d4 is an isotopically labeled variant of a lysine-specific demethylase 1 (LSD1) inhibitor, specifically designed for enhanced stability and traceability in biochemical assays. Enhanced with four deuterium atoms, this compound provides a robust tool for studying the pharmacodynamics and pharmacokinetics of LSD1 inhibitors. LSD1 is a target for drug development in various diseases, including cancer and neurological disorders, due to its role in epigenetic regulation. The deuterium atoms in GSK LSD1 Dihydrochloride-d4 reduce the rate of metabolic degradation, allowing for more precise measurement and analysis in complex biological matrices. This makes it particularly valuable for researchers conducting detailed mechanistic studies or validating drug efficacy and metabolism in preclinical and clinical trials.