For research use only. Not for therapeutic Use.
GSK137647A(CAT: I003280) emerges as a potent and selective agonist of the Free Fatty Acid Receptor 4 (FFA4). With pEC50 values of 6.3, 6.2, and 6.1 for human, mouse, and rat FFA4, respectively, this compound exhibits a high degree of affinity and activity across species. By specifically activating FFA4, GSK137647A contributes to the modulation of lipid signaling pathways and potentially impacts metabolic and inflammatory processes.
| Catalog Number | I003280 |
| CAS Number | 349085-82-1 |
| Synonyms | N-mesityl-4-methoxybenzenesulfonamide |
| Molecular Formula | C16H19NO3S |
| Purity | ≥95% |
| Target | Free Fatty Acid Receptor |
| Solubility | DMSO: ≥ 32 mg/mL, H2O: ＜ 0.06 mg/mL (Need ultrasonic and warming) |
| Storage | Store at RT |
| IC50 | 6.3/6.2/6.1 (pEC50, for human/mouse/rat FFA4) |
| InChI | InChI=1S/C16H19NO3S/c1-11-9-12(2)16(13(3)10-11)17-21(18,19)15-7-5-14(20-4)6-8-15/h5-10,17H,1-4H3 |
| InChIKey | FQUAFMNPXPXOJE-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(S(NC2=C(C)C=C(C)C=C2C)(=O)=O)C=C1 |
| Reference | <p style=/line-height:25px/> |
