GSK2200150A

• CAT Number: I012601
• CAS Number: 1443138-53-1
• Molecular Formula: C20H23NO3S
• Molecular Weight: 357.47
• Purity: ≥95%
• Synonyms: SPIRO; 1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)methyl]-6/’,7/’-dihydro-spiro[piperidine-4,4/’-[4H]thieno[3,2-c]pyran]
• Target: Bacterial
• Storage: Store at -20°C
• IUPAC Name: 1'-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)spiro[6,7-dihydrothieno[3,2-c]pyran-4,4'-piperidine]
• InChI: InChI=1S/C20H23NO3S/c1-2-17-18(23-11-10-22-17)13-15(1)14-21-7-5-20(6-8-21)16-4-12-25-19(16)3-9-24-20/h1-2,4,12-13H,3,5-11,14H2
• InChIKey: NCRPMBWORFWNGT-UHFFFAOYSA-N
• SMILES: C1COC2(CCN(CC2)CC3=CC4=C(C=C3)OCCO4)C5=C1SC=C5

GSK2200150A（Cat No.:I012601）is a potent and selective small molecule inhibitor of the PAK (p21-activated kinase) family, particularly targeting PAK1 and PAK4. It inhibits the phosphorylation of downstream signaling pathways involved in cell migration, survival, and proliferation, making it a valuable tool in cancer research and drug development. By modulating the activity of PAK, GSK2200150A holds promise in therapeutic strategies for cancer, neurodegenerative diseases, and other conditions characterized by dysregulated PAK signaling. It is widely used in preclinical studies to explore its therapeutic potential and mechanism of action.