For research use only. Not for therapeutic Use.
GSK256073 is a small-molecule inhibitor developed as part of research into potential treatments for inflammatory and autoimmune diseases. It specifically targets and inhibits phosphodiesterase 4 (PDE4), an enzyme involved in the breakdown of cyclic adenosine monophosphate (cAMP) within cells. By inhibiting PDE4, GSK256073 increases intracellular cAMP levels, which can lead to anti-inflammatory effects by modulating the release of pro-inflammatory cytokines. Although GSK256073 showed promise in preclinical studies, its development status would depend on further clinical trials to determine its safety and efficacy in treating conditions like asthma, chronic obstructive pulmonary disease (COPD), or psoriasis.
| Catalog Number | I007092 |
| CAS Number | 862892-90-8 |
| Synonyms | 8-chloro-3-pentyl-7H-purine-2,6-dione |
| Molecular Formula | C10H13ClN4O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C10H13ClN4O2/c1-2-3-4-5-15-7-6(12-9(11)13-7)8(16)14-10(15)17/h2-5H2,1H3,(H,12,13)(H,14,16,17) |
| InChIKey | CGAMDQCXAAOFSR-UHFFFAOYSA-N |
| SMILES | CCCCCN1C2=C(C(=O)NC1=O)NC(=N2)Cl |
