For research use only. Not for therapeutic Use.
GSK264220A is a potent endothelial lipase inhibitor with IC50 of 16 nM. GSK264220A has the potential to decrease the risk of cardiovascular disease[1].
| Catalog Number | I007095 |
| CAS Number | 685506-42-7 |
| Synonyms | 1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea |
| Molecular Formula | C17H21N3O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H21N3O4S/c1-13-15(19-17(21)18-14-8-4-2-5-9-14)12-16(24-13)25(22,23)20-10-6-3-7-11-20/h2,4-5,8-9,12H,3,6-7,10-11H2,1H3,(H2,18,19,21) |
| InChIKey | LVOVQRPAMXCXTM-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3 |
| Reference | [1]. Keller PM, et al. A high-throughput screen for endothelial lipase using HDL as substrate. J Biomol Screen. 2008 Jul;13(6):468-75. |
