For research use only. Not for therapeutic Use.
GSK3532795(CAT: I005970), also known as BMS-955176, is a second-generation maturation inhibitor that targets HIV-1, preventing the virus from forming mature infectious particles. It works by disrupting the final step of viral maturation, specifically by interfering with the cleavage of the Gag protein, essential for creating a functional virus. GSK3532795 is a significant compound in HIV research, offering promise for developing new antiretroviral therapies, especially for patients resistant to other treatments. Its unique mechanism of action provides insights into innovative strategies for managing HIV and improving patient outcomes in the treatment of this chronic infection.
| Catalog Number | I005970 |
| CAS Number | 1392312-45-6 |
| Synonyms | 4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[2-(1,1-dioxo-1,4-thiazinan-4-yl)ethylamino]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid |
| Molecular Formula | C42H62N2O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C42H62N2O4S/c1-28(2)31-14-19-42(43-22-23-44-24-26-49(47,48)27-25-44)21-20-40(6)33(36(31)42)12-13-35-39(5)17-15-32(29-8-10-30(11-9-29)37(45)46)38(3,4)34(39)16-18-41(35,40)7/h8-11,15,31,33-36,43H,1,12-14,16-27H2,2-7H3,(H,45,46)/t31-,33+,34-,35+,36+,39-,40+,41+,42-/m0/s1 |
| InChIKey | XDMUFNNPLXHNKA-ZTESCHFWSA-N |
| SMILES | CC(=C)C1CCC2(C1C3CCC4C(C3(CC2)C)(CCC5C4(CC=C(C5(C)C)C6=CC=C(C=C6)C(=O)O)C)C)NCCN7CCS(=O)(=O)CC7 |
