For research use only. Not for therapeutic Use.
Guanethidine (CAT: I004433) is an antihypertensive medication that belongs to the class of drugs known as sympatholytics. It works by reducing the release of norepinephrine, a neurotransmitter that plays a role in regulating blood pressure. Guanethidine acts by blocking the release of norepinephrine from nerve endings, thereby reducing its availability to interact with receptors and exerting its effects on blood vessels. By reducing the levels of norepinephrine, guanethidine helps to lower blood pressure and manage hypertension. It is typically used in the treatment of high blood pressure when other antihypertensive medications have not been effective.
| Catalog Number | I004433 |
| CAS Number | 645-43-2 |
| Synonyms | N-[2-(hexahydro-1(2H)-azocinyl)ethyl]-guanidine, monosulfate |
| Molecular Formula | C10H22N4 • H2SO4 |
| Purity | ≥95% |
| Solubility | H2O: ≥ 24 mg/mL, DMSO: ＜ 3.4 mg/mL |
| Storage | -20°C |
| IUPAC Name | 2-[2-(azocan-1-yl)ethyl]guanidine;sulfuric acid |
| InChI | InChI=1S/C10H22N4.H2O4S/c11-10(12)13-6-9-14-7-4-2-1-3-5-8-14;1-5(2,3)4/h1-9H2,(H4,11,12,13);(H2,1,2,3,4) |
| InChIKey | YUFWAVFNITUSHI-UHFFFAOYSA-N |
| SMILES | C1CCCN(CCC1)CCN=C(N)N.OS(=O)(=O)O |
| Reference | <br /> |
