Guanfacine Hydrochloride

• CAT Number: A000028
• CAS Number: 29110-48-3
• Molecular Formula: C9H10Cl3N3O
• Molecular Weight: 282.55
• Purity: ≥95%
• Synonyms: Guanfacine Hydrochloride, Guanfacine, Tenex, Intuniv
• Target: Neuronal Signaling
• Solubility: >14.1mg/mL in DMSO
• Storage: Store at -20°C
• IUPAC Name: N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride
• InChI: InChI=1S/C9H9Cl2N3O.ClH/c10-6-2-1-3-7(11)5(6)4-8(15)14-9(12)13;/h1-3H,4H2,(H4,12,13,14,15);1H
• InChIKey: DGFYECXYGUIODH-UHFFFAOYSA-N
• SMILES: C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl

Guanfacine hydrochloride（Cat No.:A000028） is a pharmaceutical compound used primarily to treat attention deficit hyperactivity disorder (ADHD) and hypertension. As a selective alpha-2 adrenergic receptor agonist, guanfacine reduces sympathetic nervous system activity, leading to lower blood pressure and improved impulse control and attention. In ADHD treatment, particularly in children, it is appreciated for its ability to improve symptoms of hyperactivity, impulsiveness, and distractibility. Guanfacine hydrochloride is often preferred for its longer duration of action and milder side effect profile compared to stimulants. It is also researched for potential benefits in other cognitive and psychiatric disorders.