For research use only. Not for therapeutic Use.
Guanidine thiocyanate is a freely soluble chaotropic agent routinely used for DNA/RNA extraction protocols.</br>Extraction of cellular DNA and RNA releases DNase and RNase proteins which function by denaturing DNA and RNA respectively. Guanidine thiocyanate is a preferred chemical to use during cell lysis because of its ability to irreversibly inactivate these degrading nucleases. In addition to its chaotropic properties, guanidine thiocyanate has also shown to inactivate enveloped viruses and some non-enveloped viruses.
| Catalog Number | R001544 |
| CAS Number | 593-84-0 |
| Molecular Formula | CN3H5 •HSCN |
| Purity | ≥95% |
| Target | Endogenous Metabolite |
| Storage | 2-8 °C |
| Reference | <p>Roberts, P. L. /Virus Inactivation by Protein Denaturants Used in Affinity Chromatography./ <em>Biologicals: Journal of the International Association of Biological Standardization</em> 35.4 (2007): 343-47. <em>Ncbi.gov</em>. 24 May 2007. Web. 12 Sept. 2012.</p></span></p> |
