GW-3333

For research use only. Not for therapeutic Use.

  • CAT Number: I007144
  • CAS Number: 212609-68-2
  • Molecular Formula: C22H36N4O4
  • Molecular Weight: 420.554
  • Purity: ≥95%
Inquiry Now

GW-3333 is a potent and selective antagonist of the angiotensin II type 1 (AT1) receptor. This compound is primarily utilized in cardiovascular research to study the role of AT1 receptors in hypertension and heart failure. By inhibiting the AT1 receptor, GW-3333 effectively reduces vasoconstriction and aldosterone secretion, offering valuable insights into the therapeutic potential of AT1 antagonists. Its high specificity and efficacy make GW-3333 a crucial tool in developing treatments for cardiovascular disorders and understanding the underlying mechanisms of hypertension.


Catalog Number I007144
CAS Number 212609-68-2
Synonyms

GW-3333; GW3333; GW 3333;;(2R,3S)-3-(Formyl-hydroxyamino)-2-(2-methyl-1-propyl)-4-methylpentanoic acid, ((1S,2S)-2-methyl-1-(2-pyridylcarbamoyl)-1-butyl)amide

Molecular Formula C22H36N4O4
Purity ≥95%
Target Metabolic Enzyme/Protease
Solubility Soluble in DMSO
Storage 0 - 4°C for short term or -20 °C for long term
IUPAC Name (2R,3S)-3-[formyl(hydroxy)amino]-4-methyl-N-[(2S,3S)-3-methyl-1-oxo-1-(pyridin-2-ylamino)pentan-2-yl]-2-(2-methylpropyl)pentanamide
InChI InChI=1S/C22H36N4O4/c1-7-16(6)19(22(29)24-18-10-8-9-11-23-18)25-21(28)17(12-14(2)3)20(15(4)5)26(30)13-27/h8-11,13-17,19-20,30H,7,12H2,1-6H3,(H,25,28)(H,23,24,29)/t16-,17+,19-,20-/m0/s1
InChIKey SMZPWUUYPYYHIV-HNJRGHQBSA-N
SMILES CCC(C)C(C(=O)NC1=CC=CC=N1)NC(=O)C(CC(C)C)C(C(C)C)N(C=O)O

Request a Quote