GW409544

• CAT Number: I007147
• CAS Number: 258345-41-4
• Molecular Formula: C31H30N2O5
• Molecular Weight: 510.59
• Purity: ≥95%
• Synonyms: GW409544; GW 409544; GW-409544.;(2S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-[[(Z)-4-oxo-4-phenylbut-2-en-2-yl]amino]propanoic acid
• Target: PPAR Agonist
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term or -20 °C for long term
• IUPAC Name: (2S)-3-[4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]-2-[[(Z)-4-oxo-4-phenylbut-2-en-2-yl]amino]propanoic acid
• InChI: InChI=1S/C31H30N2O5/c1-21(19-29(34)24-9-5-3-6-10-24)32-28(31(35)36)20-23-13-15-26(16-14-23)37-18-17-27-22(2)38-30(33-27)25-11-7-4-8-12-25/h3-16,19,28,32H,17-18,20H2,1-2H3,(H,35,36)/b21-19-/t28-/m0/s1
• InChIKey: GGUVRMBIEPYOKL-WMVCGJOFSA-N
• SMILES: CC1=C(N=C(O1)C2=CC=CC=C2)CCOC3=CC=C(C=C3)CC(C(=O)O)NC(=CC(=O)C4=CC=CC=C4)C

GW409544 is a potent and selective agonist of the peroxisome proliferator-activated receptor-gamma (PPAR-γ), a nuclear receptor involved in regulating glucose and lipid metabolism. This compound is widely used in metabolic research to investigate the role of PPAR-γ activation in insulin sensitivity, adipogenesis, and the management of type 2 diabetes. By modulating PPAR-γ activity, GW409544 provides critical insights into the development of therapeutic agents for metabolic disorders, making it a valuable tool in the study of diabetes and obesity-related conditions.