For research use only. Not for therapeutic Use.
GW856804X(CAT: I028535) is a potent and selective chemokine receptor CCR1 antagonist, extensively used in research focused on inflammatory and autoimmune disorders. By blocking CCR1 signaling, it inhibits the migration of immune cells, making it valuable for studying conditions such as rheumatoid arthritis, multiple sclerosis, and other chronic inflammatory diseases. GW856804X is also instrumental in exploring the role of CCR1 in tumor microenvironments and metastasis. With high specificity and consistent performance, this compound is an essential tool for advancing therapeutic development and understanding chemokine-mediated immune responses.
| Catalog Number | I028535 |
| Synonyms | GW-856804X; GW 856804X; GW856804X |
| Molecular Formula | C19H13ClFN3O2S2 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 3-(4-Amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c]pyridin-7-yl)benzenesulfonamide |
| InChI | InChI=1S/C19H13ClFN3O2S2/c20-15-7-11(4-5-16(15)21)14-9-27-18-13(8-24-19(22)17(14)18)10-2-1-3-12(6-10)28(23,25)26/h1-9H,(H2,22,24)(H2,23,25,26) |
| InChIKey | PILHXMMEJPSZLL-UHFFFAOYSA-N |
| SMILES | O=S(C1=CC=CC(C2=CN=C(N)C3=C2SC=C3C4=CC=C(F)C(Cl)=C4)=C1)(N)=O |
