GW9508

• CAT Number: I005314
• CAS Number: 885101-89-3
• Molecular Formula: C22H21NO3
• Molecular Weight: 347.40
• Purity: ≥95%
• Synonyms: 3-[4-[(3-phenoxyphenyl)methylamino]phenyl]propanoic acid
• Target: Membrane Transporter/Ion Channel
• Solubility: DMSO 69 mg/ml; Water <1 mg/ml
• Storage: 3 years -20C powder
• IC50: 7.32 (pEC50)
• InChI: InChI=1S/C22H21NO3/c24-22(25)14-11-17-9-12-19(13-10-17)23-16-18-5-4-8-21(15-18)26-20-6-2-1-3-7-20/h1-10,12-13,15,23H,11,14,16H2,(H,24,25)
• InChIKey: DGENZVKCTGIDRZ-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)OC2=CC=CC(=C2)CNC3=CC=C(C=C3)CCC(=O)O

GW9508（Cat No.:I005314）is a synthetic agonist of the G-protein coupled receptor (GPCR) GPR40, which is involved in regulating insulin secretion and glucose homeostasis. By activating GPR40, GW9508 enhances the release of insulin in response to glucose, making it a potential candidate for the treatment of type 2 diabetes. It has also been studied for its anti-inflammatory effects, particularly in adipose tissue, and its ability to improve metabolic parameters. GW9508 is useful in preclinical studies to explore the role of GPR40 in glucose regulation, with ongoing research into its safety and therapeutic efficacy.