H-1152 Glycyl Dihydrochloride

• CAT Number: R009434
• CAS Number: 913844-45-8
• Molecular Formula: C18H24N4O3S • 2HCl
• Molecular Weight: 449.40
• Purity: ≥95%
• Synonyms: 2-Amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]ethanone Hydrochloride; (2S)-4-(Aminoacetyl)hexahydro?-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepine Dihydrochloride
• Storage: -20°C
• IUPAC Name: 2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinolin-5-yl)sulfonyl-1,4-diazepan-1-yl]ethanone;dihydrochloride
• InChI: InChI=1S/C18H24N4O3S.2ClH/c1-13-10-20-11-15-5-3-6-16(18(13)15)26(24,25)22-8-4-7-21(12-14(22)2)17(23)9-19;;/h3,5-6,10-11,14H,4,7-9,12,19H2,1-2H3;2*1H/t14-;;/m0../s1
• InChIKey: ILDBNQGLZFSHQZ-UTLKBRERSA-N
• SMILES: C[C@H]1CN(CCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C)C(=O)CN.Cl.Cl

H-1152 Glycyl Dihydrochloride（Cat No.:R009434）is a highly selective and potent inhibitor of Rho-associated protein kinase (ROCK), known for its ability to regulate the actin cytoskeleton and cell motility. By inhibiting ROCK, H-1152 promotes vasodilation, reduces cellular contraction, and enhances endothelial function. This compound is commonly used in research related to cardiovascular diseases, neuroprotection, and cell migration. Additionally, it is valuable in studies focusing on cytoskeletal dynamics, tissue regeneration, and cancer metastasis, making it an important tool in both basic research and therapeutic development.