H-Asp(AMC)-OH

• CAT Number: M117977
• CAS Number: 133628-73-6
• Molecular Formula: C14H14N2O5
• Molecular Weight: 290.27
• Purity: ≥95%
• Synonyms: (2S)-2-amino-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoic acid
• InChI: InChI=1S/C14H14N2O5/c1-7-4-13(18)21-11-5-8(2-3-9(7)11)16-12(17)6-10(15)14(19)20/h2-5,10H,6,15H2,1H3,(H,16,17)(H,19,20)/t10-/m0/s1
• InChIKey: ARZPQBJTLVVDNP-JTQLQIEISA-N
• SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)CC(C(=O)O)N

H-Asp(AMC)-OH, a amino acid derivative, is a fluorescent dye. H-Asp(AMC)-OH dose not inhibit glycine transport at a concentration of 0.25 mM[1].

Reference

[1]. Hatanaka T, et al. Transport of amino acid-based prodrugs by the Na+- and Cl(-) -coupled amino acid transporter ATB0,+ and expression of the transporter in tissues amenable for drug delivery. J Pharmacol Exp Ther. 2004 Mar;308(3):1138-47.
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