H-LYS-THR-ASN-MET-LYS-HIS-MET-ALA-GLY-ALA-ALA-ALA-ALA-GLY-ALA-VAL-VAL-GLY-GLY-LEU-GLY-OH

• CAT Number: M094710
• CAS Number: 148439-49-0
• Molecular Formula: C80H138N26O24S2
• Molecular Weight: 1912.26
• Purity: ≥95%
• Synonyms: (3Z,5S,6Z,9Z,12Z,14S,15Z,17S,18Z,20S,21Z,24Z,26S,27Z,29S,30Z,32S,33Z,35S,36Z,39Z,41S,42Z,44S,45Z,47S,48Z,50S,51Z,53S,54Z,56S,57Z,59S,60Z,62S)-47-((1H-imidazol-5-yl)methyl)-62,66-diamino-50-(4-aminobutyl)-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,
• Target: Peptide and Derivatives
• Solubility: Soluble to 1 mg/ml in sterile water
• Storage: Desiccate at -20C
• InChI: InChI=1S/C80H138N26O24S2/c1-38(2)28-53(72(122)90-36-61(113)114)98-60(112)33-86-57(109)32-89-78(128)62(39(3)4)105-79(129)63(40(5)6)104-70(120)44(10)93-59(111)35-87-65(115)41(7)94-68(118)45(11)96-69(119)46(12)95-67(117)43(9)92-58(110)34-88-66(116)42(8)97-73(123)51(22-26-131-14)100-76(126)54(29-48-31-85-37-91-48)102-74(124)50(21-17-19-25-82)99-75(125)52(23-27-132-15)101-77(127)55(30-56(84)108)103-80(130)64(47(13)107)106-71(121)49(83)20-16-18-24-81/h31,37-47,49-55,62-64,107H,16-30,32-36,81-83H2,1-15H3,(H2,84,108)(H,85,91)(H,86,109)(H,87,115)(H,88,116)(H,89,128)(H,90,122)(H,92,110)(H,93,111)(H,94,118)(H,95,117)(H,96,119)(H,97,123)(H,98,112)(H,99,125)(H,100,126)(H,101,127)(H,102,124)(H,103,130)(H,104,120)(H,105,129)(H,106,121)(H,113,114)/t41-,42-,43-,44-,45-,46-,47+,49-,50-,51-,52-,53-,54-,55-,62-,63-,64-/m0/s1
• InChIKey: XPZWWTIIKSODDO-MBNDGZRNSA-N
• SMILES: CC(C)CC(C(=O)NCC(=O)O)NC(=O)CNC(=O)CNC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC1=CNC=N1)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CC(=O)N)NC(=O)C(C(C)O)NC(=O)C(CCCCN)N

PrP (106-126) (Cat No.: M094710) is a fragment of the prion protein, PrP, that is associated with prion diseases, such as Creutzfeldt-Jakob disease and Alzheimer’s. This particular sequence (amino acids 106 to 126) is known for its ability to form amyloid fibrils, which are implicated in the neurodegenerative effects of prion diseases. Research on PrP (106-126) focuses on understanding how prion protein misfolding contributes to disease progression and exploring potential therapeutic strategies to prevent or mitigate prion-induced neurotoxicity.