For research use only. Not for therapeutic Use.
H3B-120 (CAT: I015490) is a highly selective and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1). CPS1 is an enzyme involved in the first step of the urea cycle, which plays a crucial role in the metabolism and elimination of nitrogen waste in the body. By inhibiting CPS1, H3B-120 disrupts the urea cycle, leading to a decrease in the production of urea. This mechanism of action has potential therapeutic applications in the treatment of certain metabolic disorders and cancers where CPS1 is dysregulated.
| Catalog Number | I015490 |
| CAS Number | 2194903-42-7 |
| Molecular Formula | C₁₉H₂₄N₄O₂S |
| Purity | ≥95% |
| Target | Potassium Channel |
| Reference | [1]. Yao S, et al. Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol. 2020 Mar 19;27(3):259-268. |
