For research use only. Not for therapeutic Use.
H3B-8800 is a potent and orally active modulator of SF3B splicing. H3B-8800 interacts directly with the SF3b complex, demonstrating anti-cancer properties. H3B-8800 holds promise for studying acute myeloid leukemia (AML) with SF3B1 mutations.
| Catalog Number | I028577 |
| CAS Number | 1825302-42-8 |
| Molecular Formula | C31H45N3O6 |
| Purity | ≥95% |
| Reference | [1] Seiler M, et al. Nat Med. 2018 May;24(4):497-504. |
