For research use only. Not for therapeutic Use.
Antitumor agent-108 (compound 5) is an Hyaluronic acid (HA)-CD44 interaction inhibitor that effectively disrupts the integrity of cancer spheroids. Antitumor agent-108 also exhibits antiproliferative activity against cancer cells[1].
| Catalog Number | I041004 |
| CAS Number | 3009761-01-4 |
| Synonyms | 2-[(3,4,5-trimethoxyphenyl)methyl]-3,4-dihydro-1H-isoquinolin-5-ol |
| Molecular Formula | C19H23NO4 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H23NO4/c1-22-17-9-13(10-18(23-2)19(17)24-3)11-20-8-7-15-14(12-20)5-4-6-16(15)21/h4-6,9-10,21H,7-8,11-12H2,1-3H3 |
| InChIKey | NUVDZRTYISZXFC-UHFFFAOYSA-N |
| SMILES | COC1=CC(=CC(=C1OC)OC)CN2CCC3=C(C2)C=CC=C3O |
| Reference | [1]. Espejo-Román JM, et al. N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Eur J Med Chem. 2023 Oct 5;258:115570. |
