For research use only. Not for therapeutic Use.
Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone[1].
Halofenozide (RH-0345) reduces both growth and development of oocytes in vitro[1].
After topical application of Halofenozide (RH-0345; 5 and 10 μg) on adult females, the highest dose (10 μg) reduces significantly the reproductive parameters scored: namely the oviposition period, the fecundity and the egg viability[1].
Halofenozide at the two doses tested (5 and 10 μg) causes smaller eggs with a decrease in length, width and volume[1].
| Catalog Number | R056145 |
| CAS Number | 112226-61-6 |
| Synonyms | N’-benzoyl-N’-tert-butyl-4-chlorobenzohydrazide |
| Molecular Formula | C18H19ClN2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H19ClN2O2/c1-18(2,3)21(17(23)14-7-5-4-6-8-14)20-16(22)13-9-11-15(19)12-10-13/h4-12H,1-3H3,(H,20,22) |
| InChIKey | CNKHSLKYRMDDNQ-UHFFFAOYSA-N |
| SMILES | CC(C)(C)N(C(=O)C1=CC=CC=C1)NC(=O)C2=CC=C(C=C2)Cl |
| Reference | [1]. Faïza Taïbi, et al. Effect of ecdysone agonist RH-0345 on reproduction of mealworm, Tenebrio molitor. Comp Biochem Physiol C Toxicol Pharmacol. 2003 Jul;135C(3):257-67. |
