Halofuginone Hydrobromide

• CAT Number: R051332
• CAS Number: 64924-67-0
• Molecular Formula: C16H18Br2ClN3O3
• Molecular Weight: 495.59
• Purity: ≥95%
• Synonyms: rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone Hydrobromide; trans-(+/-)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-?piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone Monohydrobromide; RU 19110; Stenorol
• Target: TGF-beta/Smad
• Storage: 3 years -20℃ powder
• IUPAC Name: 7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one;hydrobromide
• InChI: InChI=1S/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1
• InChIKey: SJUWEPZBTXEUMU-LDXVYITESA-N
• SMILES: C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O.Br

Halofuginone Hydrobromide (Cat.No:R051332) is a derivative of Halofuginone, a natural alkaloid found in certain plants. It has been studied for its potential in treating fibrotic disorders and autoimmune diseases. Halofuginone Hydrobromide inhibits collagen synthesis and immune responses, showing promise in preclinical models for conditions like scleroderma and Crohn’s disease.