For research use only. Not for therapeutic Use.
Halofuginone hydrochloride is a synthetic derivative of febrifugine, an alkaloid originally isolated from the plant Dichroa febrifuga. It is primarily used as an anticoccidial agent in veterinary medicine to prevent and treat coccidiosis in poultry and livestock. Beyond its veterinary applications, halofuginone hydrochloride has been studied for its antifibrotic and anti-inflammatory properties in humans. It inhibits the synthesis of collagen type I and has shown potential in treating fibrotic diseases, such as scleroderma and liver fibrosis. Its multifaceted biological activities make it a compound of interest in both agriculture and medical research.
| Catalog Number | R005528 |
| CAS Number | 1217623-74-9 |
| Synonyms | 7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one;hydrochloride |
| Molecular Formula | C16H18BrCl2N3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H17BrClN3O3.ClH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1 |
| InChIKey | XFFYBQUXAJOKAL-LDXVYITESA-N |
| SMILES | C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O.Cl |
